Cheap Flights from O'Hare International Airport to Knoxville (TYS) Find and Compare the Best Airline Deals | Skyticket

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2025/10
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2025/10
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Total Fares（Round-Trip/Economy）: USD /Per Person

* Displayed fare(s) may differ from the actual search result

O'Hare－McGhee Tyson Airport
October Lowest Airfares
USD333

The airfare displayed above is for United Airlines

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O'Hare－McGhee Tyson Airport
November Lowest Airfares
USD242

The airfare displayed above is for Delta Air Lines

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O'Hare－McGhee Tyson Airport
December Lowest Airfares -----
O'Hare－McGhee Tyson Airport
January Lowest Airfares
USD191

The airfare displayed above is for American Airlines

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O'Hare－McGhee Tyson Airport
February Lowest Airfares -----

Chicago－Knoxville
Estimated Flight Time
1 Hours 34 Minutes
Chicago－Knoxville
Number of Operating Airlines
3

Operating Airlines for O'Hare－McGhee Tyson Airport Route
Non-StopAmerican Airlines

Non-StopUnited Airlines

Delta Air Lines

Other Destinations from:Chicago

O'Hare－Lansing(Capital Region)
USD286〜
O'Hare－Lexington (Kentucky)(Blue Grass)
USD189〜
O'Hare－Lafayette (Louisiana)(Lafayette Regional)
USD259〜
O'Hare－Lincoln (Nebraska)(LNK)
USD332〜
O'Hare－La Crosse (Wisconsin)(La Crosse Municipal)
USD439〜
* Fares vary in accordance to seat availability
Other Departures to: Knoxville

Dallas/Fort Worth Airport－Knoxville(McGhee Tyson)
USD339〜
Hartsfield-Jackson Atlanta Airport－Knoxville(McGhee Tyson)
USD359〜
Dallas Love Field Airport－Knoxville(McGhee Tyson)
USD408〜
William P. Hobby Airport－Knoxville(McGhee Tyson)
USD587〜
George Bush Intercontinental Airport－Knoxville(McGhee Tyson)
USD372〜
Chicago Midway Airport－Knoxville(McGhee Tyson)
USD666〜
Miami Airport－Knoxville(McGhee Tyson)
USD178〜
* Fares vary in accordance to seat availability