Cheap Flights from Des Moines International Airport to San Francisco (SFO) Find and Compare the Best Airline Deals | Skyticket

Departure Date

2025/6
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2025/6
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Total Fares（Round-Trip/Economy）: USD /Per Person

* Displayed fare(s) may differ from the actual search result

Des Moines－San Francisco Airport
June Lowest Airfares
USD349

The airfare displayed above is for Delta Air Lines

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Des Moines－San Francisco Airport
July Lowest Airfares -----

Des Moines－San Francisco Airport
August Lowest Airfares
USD376

The airfare displayed above is for Delta Air Lines

Set calendar for this month
Des Moines－San Francisco Airport
September Lowest Airfares -----
Des Moines－San Francisco Airport
October Lowest Airfares -----

Des Moines－San Francisco
Estimated Flight Time
4 Hours 36 Minutes
Des Moines－San Francisco
Number of Operating Airlines
4

Operating Airlines for Des Moines－San Francisco Airport Route
American Airlines

Alaska Airlines

Delta Air Lines

United Airlines

Other Destinations from:Des Moines

Des Moines－Las Vegas(Harry Reid)
USD265〜
Des Moines－Orlando(MCO)
USD283〜
Des Moines－Seattle(-Tacoma)
USD353〜
Des Moines－Boston(Logan)
USD291〜
Des Moines－Washington D.C(Ronald Reagan Washington National)
USD198〜
Des Moines－Washington D.C(Baltimore-Washington)
USD277〜
Des Moines－Washington D.C(Washington Dulles)
USD396〜
Des Moines－Chicago(O'Hare)
USD202〜
Des Moines－Chicago(Midway)
USD386〜
* Fares vary in accordance to seat availability
Other Departures to: San Francisco

Duluth Airport－San Francisco(SFO)
USD293〜
Detroit Metropolitan Airport－San Francisco(SFO)
USD287〜
El Paso Airport－San Francisco(SFO)
USD683〜
* Fares vary in accordance to seat availability