Cheap Flights from John Wayne Airport to Detroit (DTW) Find and Compare the Best Airline Deals | Skyticket

Departure Date

2025/10
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2025/10
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John Wayne－Detroit Metropolitan Airport
October Lowest Airfares
USD533

The airfare displayed above is for Delta Air Lines

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John Wayne－Detroit Metropolitan Airport
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John Wayne－Detroit Metropolitan Airport
December Lowest Airfares -----
John Wayne－Detroit Metropolitan Airport
January Lowest Airfares -----
John Wayne－Detroit Metropolitan Airport
February Lowest Airfares -----

Santa Ana－Detroit
Estimated Flight Time
4 Hours 18 Minutes
Santa Ana－Detroit
Number of Operating Airlines
3

Operating Airlines for John Wayne－Detroit Metropolitan Airport Route
Non-StopDelta Air Lines

American Airlines

United Airlines

Other Destinations from:Santa Ana
* Fares vary in accordance to seat availability
Other Departures to: Detroit
* Fares vary in accordance to seat availability