Cheap Flights from John Wayne Airport to Knoxville (TYS) Find and Compare the Best Airline Deals | Skyticket

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2025/6
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2025/6
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John Wayne－McGhee Tyson Airport
June Lowest Airfares
USD894

The airfare displayed above is for Delta Air Lines

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John Wayne－McGhee Tyson Airport
July Lowest Airfares
USD694

The airfare displayed above is for American Airlines

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John Wayne－McGhee Tyson Airport
August Lowest Airfares -----
John Wayne－McGhee Tyson Airport
September Lowest Airfares -----
John Wayne－McGhee Tyson Airport
October Lowest Airfares -----

Santa Ana－Knoxville
Estimated Flight Time
5 Hours 06 Minutes
Santa Ana－Knoxville
Number of Operating Airlines
3

Operating Airlines for John Wayne－McGhee Tyson Airport Route
Delta Air Lines

United Airlines

LCCAmerican Airlines

Other Destinations from:Santa Ana

John Wayne－Lincoln (Nebraska)(LNK)
USD427〜
* Fares vary in accordance to seat availability
Other Departures to: Knoxville
* Fares vary in accordance to seat availability