Cheap Flights from John Wayne Airport to Knoxville (TYS) Find and Compare the Best Airline Deals

Departure Date

2025/5
Sun	Mon	Tue	Wed	Thu	Fri	Sat
				1------	2------	3------
4------	5------	6------	7------	8------	9------	10------
11------	12------	13------	14Search	15Search	16Search	17Search
18Search	19Search	20Search	21Search	22Search	23Search	24Search
25Search	26Search	27Search	28Search	29Search	30Search	31Search

Select Return Date　　 Change Departure Date

　　Select Departure Date

Currency:US Dollar Loading Searching Fares Updating Fares

―

* Displayed fare(s) may differ from the actual search result

Other Destinations from:Santa Ana
* Fares vary in accordance to seat availability
Other Departures to: Knoxville

Savannah/Hilton Head Airport－Knoxville(McGhee Tyson)
USD682〜
Sarasota–Bradenton Airport－Knoxville(McGhee Tyson)
USD449〜
* Fares vary in accordance to seat availability

Santa AnaJohn Wayne AirportKnoxvilleMcGhee Tyson Airport