Cheap Flights from Orlando International Airport to Knoxville (TYS) Find and Compare the Best Airline Deals | Skyticket

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2025/10
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Orlando－McGhee Tyson Airport
October Lowest Airfares
USD388

The airfare displayed above is for Delta Air Lines

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Orlando－McGhee Tyson Airport
November Lowest Airfares -----

Orlando－McGhee Tyson Airport
December Lowest Airfares -----
Orlando－McGhee Tyson Airport
January Lowest Airfares -----
Orlando－McGhee Tyson Airport
February Lowest Airfares -----

Orlando－Knoxville
Estimated Flight Time
2 Hours 23 Minutes
Orlando－Knoxville
Number of Operating Airlines
3

Operating Airlines for Orlando－McGhee Tyson Airport Route
American Airlines

Delta Air Lines

United Airlines

Other Destinations from:Orlando

Orlando－Lansing(Capital Region)
USD253〜
Orlando－Lexington (Kentucky)(Blue Grass)
USD258〜
* Fares vary in accordance to seat availability
Other Departures to: Knoxville

Seattle-Tacoma Airport－Knoxville(McGhee Tyson)
USD455〜
Logan Airport－Knoxville(McGhee Tyson)
USD246〜
O'Hare Airport－Knoxville(McGhee Tyson)
USD187〜
Washington Dulles Airport－Knoxville(McGhee Tyson)
USD347〜
Baltimore-Washington Airport－Knoxville(McGhee Tyson)
USD202〜
Ronald Reagan Washington National Airport－Knoxville(McGhee Tyson)
USD204〜
Chicago Midway Airport－Knoxville(McGhee Tyson)
USD656〜
* Fares vary in accordance to seat availability