Cheap Flights from Des Moines International Airport to San Francisco (SFO) Find and Compare the Best Airline Deals | Skyticket

Departure Date

2025/4
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2025/4
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Total Fares（Round-Trip/Economy）: USD /Per Person

* Displayed fare(s) may differ from the actual search result

Des Moines－San Francisco Airport
April Lowest Airfares -----
Des Moines－San Francisco Airport
May Lowest Airfares
USD313

The airfare displayed above is for Delta Air Lines

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Des Moines－San Francisco Airport
June Lowest Airfares -----
Des Moines－San Francisco Airport
July Lowest Airfares -----
Des Moines－San Francisco Airport
August Lowest Airfares -----

Des Moines－San Francisco
Estimated Flight Time
4 Hours 36 Minutes
Des Moines－San Francisco
Number of Operating Airlines
4

Operating Airlines for Des Moines－San Francisco Airport Route
American Airlines

Alaska Airlines

Delta Air Lines

United Airlines

Other Destinations from:Des Moines

Des Moines－Las Vegas(Harry Reid)
USD367〜
Des Moines－Seattle(-Tacoma)
USD385〜
Des Moines－Boston(Logan)
USD285〜
Des Moines－Washington D.C(Baltimore-Washington)
USD271〜
Des Moines－Washington D.C(Washington Dulles)
USD388〜
Des Moines－Washington D.C(Ronald Reagan Washington National)
USD434〜
Des Moines－Chicago(O'Hare)
USD213〜
* Fares vary in accordance to seat availability
Other Departures to: San Francisco

Duluth Airport－San Francisco(SFO)
USD286〜
Detroit Metropolitan Airport－San Francisco(SFO)
USD288〜
El Paso Airport－San Francisco(SFO)
USD668〜
* Fares vary in accordance to seat availability