Cheap Flights from John Wayne Airport to Columbia (South Carolina) (CAE) Find and Compare the Best Airline Deals

Departure Date

2025/5
Sun	Mon	Tue	Wed	Thu	Fri	Sat
				1------	2------	3------
4------	5------	6------	7------	8------	9------	10------
11------	12------	13------	14------	15------	16------	17------
18------	19------	20Search	21Search	22Search	23Search	24Search
25Search	26Search	27Search	28Search	29Search	30Search	31Search

Select Return Date　　 Change Departure Date

　　Select Departure Date

Currency:US Dollar Loading Searching Fares Updating Fares

―

* Displayed fare(s) may differ from the actual search result

Other Destinations from:Santa Ana

John Wayne－Cincinnati(/Northern Kentucky)
USD407〜
John Wayne－Daytona Beach(DAB)
USD308〜
* Fares vary in accordance to seat availability
Other Departures to: Columbia (South Carolina)
* Fares vary in accordance to seat availability

Santa AnaJohn Wayne AirportColumbia (South Carolina)Columbia Metropolitan Airport